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The Chemistry and Biology of Nitroxyl (HNO). Fabio Doctorovich, Patrick Farmer, Marcelo A. Marti

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ISBN: 9780128009345 | 370 pages | 10 Mb

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The Chemistry and Biology of Nitroxyl (HNO) Fabio Doctorovich, Patrick Farmer, Marcelo A. Marti
Publisher: Elsevier Science

It is clear that HNO possesses unique and a potentially important biological activity that is distinct from NO (and other nitrogen oxides). Nitroxyl (HNO/NO-), the reduced form of nitric oxide, has gained attention unique donors for the detailed study of HNO chemistry and biology. The chemistry and biology of nitroxyl (HNO) : a chemically unique species with novel and important biological activity. Recent discoveries of novel and potentially important biological activity have spurred interest in the chemistry and biochemistry of nitroxyl (HNO). Nitroxyl (HNO) is chemically unique and biologically important. Nitroxyl (HNO), the one-electron reduced form of nitric oxide (NO), shows a distinct chemical and biological profile from that of NO. Herein, we review these developments in HNO chemistry and biology. The Physiological Chemistry and Biological Activity of Nitroxyl (HNO): The Neglected, Misunderstood, and Enigmatic Nitrogen Oxide. The chemical biology of HNO, is to determine the pharmacological and possible endogenous production of this species in vivo. Acyloxy nitroso compounds hydrolyze to nitroxyl (HNO), a nitrogen monoxide with distinct chemistry and biology. Hydride and hydrogen oxonitrate. Regardless, the majority of the recentchemical and biological literature utilizes the term “nitroxyl” when referring toHNO. NITROXYL (HNO): Chemistry, Biochemistry, and Pharmacology of biological action.

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